منابع مشابه
Chemotherapy for Extracranial Germ Cell Tumours in Paediatric, Adolescent, and Young Adult Patients
Extracranial germ cell tumours (GCT) are derived from dysregulated, unipotent to totipotent, primordial germ cells and can arise from heterogeneous sites and occur across a broad age range of patients. Although healthcare professionals in the paediatric and adult medical fields collaborate closely, discrepancies in the staging system and risk-assignment used still exist. Treatment outcomes are ...
متن کاملManagement of ovarian germ cell tumours.
Malignant ovarian germ cell tumours are rare but they occur in women with a mean age of 19 years. It is important that these young patients are not subjected to radical surgery. In most of these patients, they can be cured with either surgery alone and careful surveillance with a combination of clinical examination, computer tomography scanning and serial serum tumour markers. Almost all of tho...
متن کاملPathogenesis of testicular germ cell tumours.
Human germ cell tumours comprise a heterogeneous group of neoplasms. In the testis, three entities are distinguished, the teratomas-yolk sac tumours of the infantile testis, the seminomas and nonseminomas of adolescents and adults, and the spermatocytic seminomas. Studies on epidemiology, histology, clinical behaviour, and chromosomal constitution of these tumours support the concept of distinc...
متن کاملImaging of testicular germ cell tumours
In testicular germ cell tumour (GCT), imaging plays a central role in assessment of tumour bulk, sites of metastases, monitoring response to therapy, surgical planning and accurate assessment of disease at relapse. The primary modality used for imaging patients with GCT is computed tomography (CT) but plain film radiography, ultrasound, magnetic resonance imaging (MRI) and positron emission tom...
متن کاملPaediatric brain tumours.
Brain tumours constitute the most frequent solid tumour in childhood. At approximately 20% of paediatric malignant disease they remain uncommon with incidence of 2-3 per 100,000. Glial tumours represent over half of brain tumours in children, although in comparison with adult gliomas, where high grade tumours predominate, low grade tumours are more frequent. These characteristically include cys...
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ژورنال
عنوان ژورنال: The Lancet Oncology
سال: 2016
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(15)00545-8